Upset picks are in italics.
Thursday
Middle Tennessee at Western Kentucky - Hilltoppers by 9
Temple at Tulsa - Golden Hurricane by 10.5
Jacksonville State at Sam Houston - Gamecocks by 8
Detroit at Green Bay - Lions by 5
Friday
Louisville at NC State - Cardinals by 5
(10) Utah at (19) Oregon State - Beavers by 9.5
Louisiana Tech at UTEP - Miners by 1.5
Cincinnati at BYU - Cougars by 1.5
Saturday
(6) Penn State at Northwestern - Nittany Lions by 13.5
(8) USC at Colorado - Buffaloes by 8
(22) Florida at Kentucky - Wildcats by 4.5
Texas A&M vs. Arkansas - Aggies by 14.5
Louisiana at Minnesota - Gophers by 6.5
Utah State at UConn - Aggies by 10.5
Clemson at Syracuse - Orange by 10.5
UAB at Tulane - Green Wave by 21.5
South Alabama at James Madison - Dukes by 11.5
Buffalo at Akron - Zips by 7.5
Eastern Michigan at Central Michigan - Chippewas by 10
Virginia at Boston College - Eagles by 4
Miami (OH) at Kent State - Redhawks by 16.5
Arizona State at California - Bears by 31.5
(1) Georgia at Auburn - Tigers by 6.5
(2) Michigan at Nebraska - Wolverines by 13
(24) Kansas at (3) Texas - Longhorns by 26
Indiana at Maryland - Terrapins by 19.5
Illinois at Purdue - Boilermakers by 4
Wagner at Rutgers - Scarlet Knights by 29
Bowling Green at Georgia Tech - Yellowjackets by 16.5
Houston at Texas Tech - Red Raiders by 13.5
Baylor at UCF - Knights by 18.5
Arkansas State at UMass - Minutemen by 5
South Florida at Navy - Midshipmen by 7
Old Dominion at Marshall - Thundering Herd by 16
Ball State at Western Michigan - Broncos by 6.5
Northern Illinois at Toledo - Rockets by 20
(23) Missouri at Vanderbilt - Tigers by 7
Boise State at Memphis - Tigers by 13
Hawaii at UNLV - Rebels by 17.5
New Mexico at Wyoming - Cowboys by 11
(13) LSU at (20) Ole Miss - Rebels by 15.5
(9) Oregon at Stanford - Ducks by 23.5
Iowa State at (14) Oklahoma - Sooners by 31.5
East Carolina at Rice - Owls by 9.5
Abilene Christian at North Texas - Mean Green by 9
Coastal Carolina at Georgia Southern - Eagles by 10
Troy at Georgia State - Panthers by 13.5
Texas State at Southern Miss - Golden Eagles by 1.5
Utah Tech at Colorado State - Rams by 24
(11) Notre Dame at (17) Duke - Blue Devils by 4
South Carolina at (21) Tennessee - Volunteers by 10.5
Michigan State at Iowa - Hawkeyes by 12.5
Charlotte at SMU - Mustangs by 17
Pittsburgh at Virginia Tech - Hokies by 1
West Virginia at TCU - Horned Frogs by 12.5
Appalachian State at UL Monroe - Mountaineers by 8.5
San Diego State at Air Force - Falcons by 19
(12) Alabama at Mississippi State - Crimson Tide by 16.5
(7) Washington at Arizona - Huskies by 19
Nevada at (25) Fresno State - Bulldogs by 26
Sunday
Atlanta vs. Jacksonville - Falcons by 0.5
Miami at Buffalo - Bills by 2
Denver at Chicago - Broncos by 8.5
Baltimore at Cleveland - Browns by 3
Cincinnati at Tennessee - Bengals by 11.5
LA Rams at Indianapolis - Rams by 2
Tampa Bay at New Orleans - Saints by 5.5
Washington at Philadelphia - Eagles by 14
Minnesota at Carolina - Panthers by 1
Pittsburgh at Houston - Steelers by 0.5
Las Vegas at LA Chargers - Chargers by 7
Arizona at San Francisco - 49ers by 17
New England at Dallas - Cowboys by 5
Kansas City at NY Jets - Chiefs by 6.5
Monday
Seattle at NY Giants - Seahawks by 7
Results
NCAA: 52-15 (.776) 257-64 overall (.801)
Upsets: 3-8 (.273) 12-28 overall (.300)
NFL: 11-5 (.688) 25-23 overall (.521)
Upsets: 2-2 (.500) 5-9 overall (.357)